Vitamin D for treatment of scleroderma

eileen · 08-13-2007, 04:52 PM

P.G. Humbert, Department of Dermatology, Centre Hospitalier Universitaire St-Jacques, 25030 Besançon Cédex, France.Summary1,25-Dihydroxyvitamin D3 [1,25(OH)2 D3] may be an immunomodulatory drug which could have a role in controlling collagen deposition, and inducing reversal of fibrosis in some tissues. These observations prompted a study of the possible use of this hormone for the treatment of scleroderma. A 35-year-old woman, who had been suffering from localized scleroderma for 2 years, was given oral 1,25(OH) 2 D3 for 6 months. The effects of the treatment were evaluated using clinical and physical measurements (skin thickness, extensibility properties of the skin). The evolution of the patient's condition during the 6-month therapy suggests that 1,25(OH)2 D3 is beneficial in localized scleroderma. The mechanisms of action are discussed in relation to the literature, which suggests both immunoregulatory and inhibitory effects on fibroblast growth.

SOURCE: http://www.blackwell-synergy.com/doi...ournalCode=ced

Gidget · 08-13-2007, 06:22 PM

Why is there two threads with the same stuff in it ??

movieking · 08-13-2007, 06:24 PM

This one is in the Positive UV forum

Gidget · 08-13-2007, 06:29 PM

So why is there another one in another forum ?

movieking · 08-13-2007, 06:36 PM

Not speaking for Eileen but I assume she felt this was a topic that should have it's own thread in this forum. Someone else asked a question in another thread that sent Eileen on a search for what she posted here.

tmmacav4 · 08-13-2007, 06:43 PM

Im the one that posted the other thread but I was asking if UV was a positive thing for scleroderma or not. Im taking it that its a positive thing.

eileen · 08-13-2007, 07:29 PM

yes it is a positive treatment for it, movieking is right now if someone does a search for the topic in the future they can find it. :)

08-13-2007, 04:52 PM	#1 (permalink)
eileen kiss me I'm Derf Join Date: Feb 10 2005 Posts: 6,818 Rep Power: 17	Vitamin D for treatment of scleroderma P.G. Humbert, Department of Dermatology, Centre Hospitalier Universitaire St-Jacques, 25030 Besançon Cédex, France.Summary1,25-Dihydroxyvitamin D3 [1,25(OH)2 D3] may be an immunomodulatory drug which could have a role in controlling collagen deposition, and inducing reversal of fibrosis in some tissues. These observations prompted a study of the possible use of this hormone for the treatment of scleroderma. A 35-year-old woman, who had been suffering from localized scleroderma for 2 years, was given oral 1,25(OH) 2 D3 for 6 months. The effects of the treatment were evaluated using clinical and physical measurements (skin thickness, extensibility properties of the skin). The evolution of the patient's condition during the 6-month therapy suggests that 1,25(OH)2 D3 is beneficial in localized scleroderma. The mechanisms of action are discussed in relation to the literature, which suggests both immunoregulatory and inhibitory effects on fibroblast growth. SOURCE: http://www.blackwell-synergy.com/doi...ournalCode=ced

08-13-2007, 06:22 PM	#2 (permalink)
Gidget J'aime Derf!! Join Date: Jul 26 2005 Location: Québec, Canada Posts: 8,523 Rep Power: 12	Re: Vitamin D for treatment of scleroderma Why is there two threads with the same stuff in it ?? __________________

08-13-2007, 06:24 PM	#3 (permalink)
movieking Police Department Join Date: Aug 12 2004 Location: Eastern NC Age: 43 Posts: 2,743 Rep Power: 13	Re: Vitamin D for treatment of scleroderma This one is in the Positive UV forum __________________ http://www.1strunvideo.formovies.com http://www.amazon.com/shops/1strunvideo

08-13-2007, 06:29 PM	#4 (permalink)
Gidget J'aime Derf!! Join Date: Jul 26 2005 Location: Québec, Canada Posts: 8,523 Rep Power: 12	Re: Vitamin D for treatment of scleroderma So why is there another one in another forum ? __________________

08-13-2007, 06:36 PM	#5 (permalink)
movieking Police Department Join Date: Aug 12 2004 Location: Eastern NC Age: 43 Posts: 2,743 Rep Power: 13	Re: Vitamin D for treatment of scleroderma Not speaking for Eileen but I assume she felt this was a topic that should have it's own thread in this forum. Someone else asked a question in another thread that sent Eileen on a search for what she posted here. __________________ http://www.1strunvideo.formovies.com http://www.amazon.com/shops/1strunvideo

08-13-2007, 06:43 PM	#6 (permalink)
tmmacav4 Join Date: Apr 20 2007 Location: michigan Posts: 96 Rep Power: 0	Re: Vitamin D for treatment of scleroderma Im the one that posted the other thread but I was asking if UV was a positive thing for scleroderma or not. Im taking it that its a positive thing.

08-13-2007, 07:29 PM	#7 (permalink)
eileen kiss me I'm Derf Join Date: Feb 10 2005 Posts: 6,818 Rep Power: 17	Re: Vitamin D for treatment of scleroderma yes it is a positive treatment for it, movieking is right now if someone does a search for the topic in the future they can find it. :)

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